Learn about this type of breast cancer and how it compares to other types. Find out how subtypes, grades and stages affect prognosis and treatment.
Update Date: 09.06.2026
Invasive ductal carcinoma (IDC) is a kind of breast cancer. It causes a growth of cells in the tubes that can carry breast milk to the nipple. These tubes are called ducts.
Invasive ductal carcinoma is an invasive cancer, which means that the cancer cells have broken through the duct and grown into the surrounding breast tissue. The cells can spread to the lymph nodes and other parts of the body. This is different from ductal carcinoma in situ (DCIS). DCIS happens when cancer cells form inside a duct but haven't grown outside of it. DCIS is a noninvasive form of ductal carcinoma.
Invasive ductal carcinoma, also called infiltrating ductal carcinoma, is the most common type of breast cancer. Most breast cancers are invasive ductal carcinomas. The other main type of breast cancer is invasive lobular carcinoma. It forms in the milk-producing glands in the breast, called lobules.
Compared with the lobular type, invasive ductal carcinoma is more likely to cause a lump in the breast. It's also more likely to be detected on an imaging test, such as a mammogram.
There are many treatment options for invasive ductal carcinoma. Care is often tailored to your specific situation, and advances in treatment continue to expand those options. Many people who receive this diagnosis are cured. When a cure is not possible, treatments may help control the cancer and help you live longer.
Breast cancers, including invasive ductal carcinomas, are often grouped into subtypes based on the results of tests on the cancer cells. Lab tests can show whether the cells use hormones or a protein called human epidermal growth factor receptor 2 (HER2) to help them grow. Whether the cancer uses one, both or none of these determines the type.
Hormone receptor (HR) positive invasive ductal carcinomas use the hormones estrogen and progesterone to help them grow. If testing finds the cancer cells have proteins called receptors for one or both hormones, the cancer is HR positive. HR-positive cancers tend to grow slowly and respond well to estrogen blocker therapy.
HER2-positive invasive ductal carcinoma makes extra HER2 protein and uses it to help fuel the cancer growth. Healthy breast cells make some HER2, but the cancer cells can make a lot more. If tests detect extra HER2 in the cancer cells or extra copies of the genes that make HER2, the cancer is HER2 positive.
HER2-positive breast cancers tend to grow quickly. But there are many treatments that can target HER2.
HER2-negative invasive ductal carcinoma doesn't make extra HER2. These cancers don't respond to treatment with medicines that target HER2.
Breast cancers that make a low level of HER2 are sometimes called HER2 low or HER2 ultralow. These cancers don't make enough HER2 to be considered HER2 positive, but they may respond to treatment with medicines that target HER2.
Triple-positive invasive ductal carcinoma has hormone receptors and makes extra HER2. These cancers respond to treatment with estrogen blocker therapy and to medicines that target HER2. Both approaches are often used to treat these cancers.
Triple-negative invasive ductal carcinoma doesn't have hormone receptors and doesn't make extra HER2. These cancers tend to grow quickly and are often diagnosed at a later stage. They don't respond to treatment with estrogen blocker therapy or medicines that target HER2. Triple-negative breast cancers respond to chemotherapy and may benefit from treatment with immunotherapy.
Invasive ductal carcinoma (IDC) doesn't always cause symptoms at first. Like other types of breast cancer, it may be found on a screening test, such as a mammogram, before it ever causes symptoms.
When they happen, invasive ductal carcinoma symptoms may include:
Compared with other types of breast cancer, invasive ductal carcinoma is more likely to form a lump in the breast tissue. The other main type of breast cancer, invasive lobular carcinoma, often doesn't cause a lump you can feel.
If you find a lump or other change in your breast, make an appointment with a doctor or other healthcare professional. Don't wait for your next mammogram. Report any changes in your breasts even if a recent mammogram showed there was no breast cancer.
The exact cause of invasive ductal carcinoma (IDC) isn't known. Research has found a link between invasive ductal carcinoma and a family history of breast cancer, obesity and drinking alcohol. But it's not clear why some people who have all these risk factors don't get cancer and some people without any risk factors do. It's likely that invasive ductal carcinoma is caused by a complex mix of your genetic makeup and the world around you.
Invasive ductal carcinoma starts when something changes the DNA inside cells within a milk duct. A cell's DNA holds the instructions that tell a cell what to do. In healthy cells, the DNA gives instructions to multiply at a set rate. The instructions also tell the cells to die off at a set time. In cancer cells, the changes to the DNA alter the instructions for multiplying and dying. The result is that the cancer cells multiply faster than healthy cells. And they can keep living when healthy cells would die. This causes too many cells in the area.
The cancer cells might form a growth, called a tumor, inside the milk duct. In invasive ductal carcinoma, the tumor grows beyond the duct and into the nearby breast tissue. The tumor can take over the local blood supply. Over time, cancer cells can break away and spread to other parts of the body. When cancer spreads, it's called metastatic cancer. Invasive ductal carcinoma most often spreads to the bones, lungs, liver and brain.
Risk factors for invasive ductal carcinoma are the same as the risk factors for breast cancer in general. Factors that may increase the risk of breast cancer include:
You can take steps to help lower your risk of invasive ductal carcinoma (IDC) and other types of breast cancer.
Talk with your doctor or other healthcare professional about when to begin breast cancer screening. Ask about the benefits and risks of screening. Together, you can decide what breast cancer screening tests are right for you.
Do occasional breast self-exams so that you know what your breasts typically feel like. If there is a new change, a lump or something not typical in your breasts, report it to a healthcare professional right away.
Breast awareness through self-exams can't prevent breast cancer. But it may help you to better understand the look and feel of your breasts. This might make it more likely that you'll notice if something changes.
If you choose to drink alcohol, limit how often you drink and keep the amount small. For overall health, drink one or fewer drinks a day. Do not drink every day. The less you drink, the better.
For breast cancer prevention, there is no safe amount of alcohol. So if you're concerned about your breast cancer risk, you may choose to not drink alcohol.
Aim for at least 30 minutes of exercise on most days of the week. If you haven't been active lately, ask a healthcare professional whether it's OK and start slowly.
Hormone therapy that uses a combination of estrogen and progesterone may increase the risk of breast cancer. Talk with a healthcare professional about the benefits and risks of hormone therapy.
If your weight is healthy, work to maintain that weight. If you need to lose weight, ask a healthcare professional about healthy ways to lower your weight. In general, try to eat fewer calories and slowly increase how much you exercise.
If you have a family history of breast cancer or think that you may have an increased risk of breast cancer, talk about it with your healthcare professional. Preventive medicines, surgery and more-frequent screening may be options for people with a high risk of breast cancer.
A diagnosis of invasive ductal carcinoma (IDC) may begin with an exam and a discussion of your symptoms. Sometimes the diagnosis starts when an imaging test, such as a mammogram, finds something concerning in a breast. To confirm whether there is cancer or not, your healthcare professional may recommend a procedure called a biopsy to remove breast tissue for testing. While many tests can spot something in the breast that may be cancer, a biopsy is the only test that can say whether you have invasive ductal carcinoma.
During a breast exam, a healthcare professional looks at the breasts for anything that's not typical. This might include changes in the skin or to the nipple. Then the health professional feels the breasts for lumps. The health professional also feels along the collarbones and around the armpits for lumps.
A mammogram is an X-ray of the breast tissue. Mammograms are commonly used to screen for breast cancer. If a screening mammogram finds something concerning, you might have another mammogram to look at the area more closely. This more-detailed mammogram is called a diagnostic mammogram. It's often used to look closely at both breasts.
On a mammogram, invasive ductal carcinoma typically looks like a growth with irregular borders.
Ultrasound uses sound waves to make pictures of structures inside the body. A breast ultrasound may give your healthcare team more information about a breast lump. For example, an ultrasound might show whether the lump is a solid mass or a fluid-filled cyst. The healthcare team uses this information to decide what tests you might need next.
On a breast ultrasound, invasive ductal carcinoma typically looks like a dark spot with an irregular border. The ultrasound may show thin lines extending from the edge of the cancer.
MRI machines use a magnetic field and radio waves to create pictures of the inside of the body. A breast MRI can make more-detailed pictures of the breast. Sometimes this method is used to look closely for any other areas of cancer in the affected breast. It also might be used to look for cancer in the other breast. Before a breast MRI, you usually receive an injection of contrast material. The contrast helps the tissue show up better in the images.
A biopsy is a procedure to remove a sample of tissue for testing in a lab. For a breast biopsy, a healthcare professional puts a needle through the skin and into the breast tissue. The health professional guides the needle using images created with X-rays, ultrasound or another type of imaging. Once the needle reaches the right place, the health professional uses the needle to draw out tissue from the breast. A marker may be placed in the spot where the tissue sample was removed. This small metal marker shows up on imaging tests. It helps your healthcare team mark the area of concern.
The tissue sample from a biopsy goes to a lab for testing. Tests can show whether the cells in the sample are cancerous. Other tests give more details about the cells. The testing is done by pathologists. Pathologists are doctors who look for disease in cells, fluids and tissue removed from the body.
Results are often given in a pathology report. The results may show:
The healthcare team uses the results from lab tests to decide on the cancer's stage, understand the prognosis and make a treatment plan.
Once your healthcare team diagnoses invasive ductal carcinoma, you may have other tests to figure out the extent of the cancer. This is called the cancer's stage. Your healthcare team uses your cancer's stage to understand your prognosis.
Complete information about your cancer's stage may not be available until after breast cancer surgery.
Tests and procedures used to stage breast cancer may include:
Not everyone needs all of these tests. Your healthcare team picks the right tests based on your specific situation.
Invasive ductal carcinoma uses the same stages as other types of breast cancer. Breast cancer stages range from 0 to 4. A lower number means the cancer is less advanced and more likely to be cured. As the cancer grows into the breast tissue and gets more advanced, the stages get higher.
A cancer's grade is a number that tells the healthcare team how different the cancer cells look from healthy cells. The grades of invasive ductal carcinoma (IDC) go from 1 to 3.
To decide on the grade, doctors in the lab, called pathologists, use a microscope to look at the cancer cells from a biopsy. If the cancer cells look similar to healthy cells, then the cancer cells are low grade. Low-grade cancer grows slowly. If the cancer cells look very different from healthy cells, then the cancer cells are high grade. High-grade cancer grows quickly.
The grades of invasive ductal carcinoma include:
The grade helps the healthcare team understand the prognosis and make a treatment plan. High-grade cancers are more likely to spread, so they may need more intense treatment. Grade 1 or 2 invasive ductal carcinoma cells are more likely to have hormone receptors and respond to estrogen blocker therapy. Grade 3 cancers are more likely to respond to chemotherapy.
Invasive ductal carcinoma (IDC) treatment often involves surgery to remove the cancer. Other treatment options include radiation therapy, chemotherapy, estrogen blocker therapy, targeted therapy and immunotherapy. Most people have more than one treatment.
Invasive ductal carcinoma treatment is similar to treatment for other types of breast cancer. There are no treatments that are specific to invasive ductal carcinoma. Your treatment options depend more on the stage of your cancer, the hormone receptor status and the HER2 status.
Most people with stage 1 or stage 2 invasive ductal carcinoma will have surgery as the first treatment. Most also will have other treatments after surgery, such as radiation, chemotherapy or estrogen blocker therapy. These other treatments kill any cancer cells that might be left after surgery and lower the risk that the cancer will come back.
Sometimes treatment starts with medicines. Your care team might recommend this if you have a stage 3 invasive ductal carcinoma that has grown large or spread to the lymph nodes. Using medicine first may shrink the cancer so that surgery is possible or so that you might consider a less invasive surgery. It also gives your care team a chance to see how the cancer responds to medicines. The response tells the care team about your prognosis and helps them make decisions about the next steps.
For a stage 4 invasive ductal carcinoma that has spread to other parts of the body, treatment uses medicines. Surgery usually isn't used to remove the cancer in the breast if the cancer has spread.
There are many options for breast cancer treatment. You don't have to sort through them on your own. Your healthcare team can help explain your options and work with you to choose a treatment plan that fits your needs and goals. Consider seeking a second opinion from a breast specialist in a breast center or clinic. Some people also find it helpful to talk with breast cancer survivors who have faced similar decisions.
Breast cancer surgery typically involves a procedure to remove the breast cancer and, sometimes, a procedure to remove some nearby lymph nodes. The main surgical procedures used to treat invasive ductal carcinoma include:
For early-stage invasive ductal carcinoma, lumpectomy followed by radiation has the same survival rate as mastectomy. The type of cancer doesn't affect which procedure you should have. The decision depends more on your personal preferences and the details of your cancer. Lumpectomy is preferred for small cancers in people who are willing to have radiation. Lumpectomy is typically used when there is only one small area of cancer in the breast. Mastectomy is preferred for larger cancers or when there are multiple areas of cancer in the breast. Mastectomy might be used in those who don't want or can't have radiation.
You may choose to have breast reconstruction after mastectomy surgery. Breast reconstruction is surgery to restore the shape to the breast. Options might include reconstruction with a breast implant or reconstruction using your own tissue. Consider asking for a referral to a plastic surgeon before your breast cancer surgery.
Radiation therapy treats cancer with powerful energy beams. The energy can come from X-rays, protons or other sources.
Radiation therapy for breast cancer often uses external beam radiation. During this type of radiation therapy, you lie on a table while a machine moves around you. The machine directs radiation to precise points on your body.
Radiation therapy is often used after surgery for invasive ductal carcinoma. It can kill any cancer cells that might be left after surgery. The radiation lowers the risk of the cancer coming back.
Chemotherapy treats cancer with strong medicines. Many chemotherapy medicines exist. Chemotherapy for breast cancer often involves a combination of medicines. Most are given through a vein. Some are available in pill form.
Chemotherapy is often used after surgery to treat invasive ductal carcinoma. It can kill any cancer cells that might remain and lower the risk of the cancer coming back.
Sometimes chemotherapy is given before surgery. This may help shrink the cancer so that surgery is possible or so that you might consider a less invasive surgery. It also gives the care team a chance to see how the cancer responds to medicines.
When the cancer spreads to other parts of the body, chemotherapy can help control it. Chemotherapy may relieve symptoms of an advanced cancer, such as pain.
Estrogen blocker therapy treats breast cancer that is sensitive to hormones. This means the cancer cells have proteins called receptors. The receptors bind to the hormones estrogen and progesterone. The cancer grows in response to these hormones. Healthcare professionals call these cancers hormone receptor positive. Most breast cancers, including most invasive ductal carcinomas, are sensitive to hormones.
Estrogen blocker therapy also is called endocrine therapy and hormone therapy for breast cancer.
Estrogen blocker therapy treatments can include:
Estrogen blocker therapy often is used after surgery and other treatments. It can lower the risk that the cancer will come back.
If the cancer spreads to other parts of the body, estrogen blocker therapy can help control it.
Targeted therapy uses medicines that attack specific chemicals in the cancer cells. By blocking these chemicals, targeted treatments can cause cancer cells to die.
Some treatments target cancer cells that make extra HER2. Breast cancer that makes extra HER2 is called HER2-positive breast cancer. Other targeted therapy medicines attack other proteins in the body that help cancer cells grow. Your cancer cells may be tested to see whether these medicines might help you.
Targeted therapy medicines may be used before surgery to shrink the cancer and make it easier to remove. They also may be used after surgery to lower the risk that the cancer will come back.
Some targeted therapy medicines are used only when the cancer has spread to other parts of the body.
Immunotherapy is a treatment with medicine that helps the body's immune system to kill cancer cells. The immune system fights off diseases by attacking germs and other cells that shouldn't be in the body. Cancer cells survive by hiding from the immune system. Immunotherapy helps the immune system cells find and kill the cancer cells.
Immunotherapy might be an option for treating invasive ductal carcinoma that's triple negative. Triple-negative breast cancer means that the cancer cells don't have hormone receptors and don't make extra HER2. This treatment may be used before and after surgery.
Learning you have invasive ductal carcinoma (IDC) can be unexpected, and it's natural to have questions about what comes next. You may be receiving a lot of information and facing decisions about surgery, radiation and medical treatments. It's common to have a range of feelings that may change from day to day, and it can take time to process everything. As you move forward, here are some ideas that might be helpful.
If you'd like to know more about your breast cancer, ask your healthcare team for the details. Write down the type, stage and hormone receptor status. Ask for good sources of information where you can learn more about your treatment options.
Knowing more about your cancer and your options may help you feel more confident when making treatment decisions. Still, some people don't want to know the details of their cancer. If this is how you feel, let your care team know that too.
You may find it helpful and encouraging to talk to others who have been diagnosed with breast cancer. Ask your healthcare team about support groups in your area, or contact the American Cancer Society or another cancer organization in your area to find resources. Find support online through Mayo Clinic Connect, a community where you can connect with others for support, practical information and answers to everyday questions.
Finding someone who is willing to listen to you talk about your hopes and fears can be helpful as you manage a cancer diagnosis. This could be a friend or family member. A counselor, medical social worker or clergy member also may offer helpful guidance and care.
Make an appointment with a doctor or other healthcare professional if you have any symptoms that worry you. If an exam or imaging test shows you might have breast cancer, your healthcare team will likely refer you to a specialist.
Specialists who care for people with breast cancer include:
Your time with your healthcare professional is limited. Prepare a list of questions so that you can make the most of your time together. List your questions from most important to least important in case time runs out. For breast cancer, some basic questions to ask include:
In addition to the questions that you've prepared, don't hesitate to ask other questions you think of during your appointment.
Be prepared to answer some questions about your symptoms and your health, such as:
Staging is a way to describe the size of the cancer and whether it has spread. Staging helps your healthcare team understand your prognosis. It also helps your team create a treatment plan that fits your cancer. The stages of invasive ductal carcinoma (IDC) are the same as the stages used for other types of breast cancer.
To stage the breast cancer, the healthcare team collects as much information about the cancer as possible. The information comes from the exams and imaging tests you've had, as well as the biopsy report from the pathologist.
Information used in staging includes:
The process of breast cancer staging can take place at different times after diagnosis and around treatment. Your stage may change as your care team gets more information about your cancer.
Healthcare professionals use different types of stages at different times.
Because there are several types of stages that consider different factors, the stages of breast cancer can be confusing and complicated. Ask your healthcare team to explain your stage and what it means for your treatment.
Anatomic staging is the simplest form of breast cancer staging. To decide on the anatomic stage, the healthcare team uses the size of the cancer and whether it has spread. Using this type of staging, the stages go from 0 to 4.
The anatomic stage may be the first stage your healthcare team talks about after your diagnosis. The stage may change as your team gets more information about your cancer, such as the hormone receptor status.
The survival rates for invasive ductal carcinoma (IDC) and other types of breast cancer are quite good, especially when the cancer is caught early. Most people with this diagnosis have an early-stage cancer and good prognosis. Many are cured. Even when a cure isn't possible, treatments often can slow the cancer's growth and extend your life.
Cancer survival rates come from studying many people with the same cancer to see how many are living five years after diagnosis. The survival rate can give you an idea about survival for people in your situation. But the numbers can't predict your personal chances of survival.
Survival rates for invasive ductal carcinoma are the same as survival rates for breast cancer in general, since most breast cancers are invasive ductal carcinomas.
The U.S. National Cancer Institute (NCI) tracks cancer survival rates in the United States. NCI breaks down the rates by how far the cancer has spread, rather than by stage.
These are the survival rates for breast cancer in general. Survival rates vary greatly depending on whether the cancer cells have hormone receptors or make extra HER2.
Cancer prognosis describes how likely it is that a cancer can be treated successfully or cured. It is based on the details of your cancer, as well as your overall health. If you want to understand your personal prognosis, talk with your healthcare team. Your team can walk you through the factors they consider and explain what those mean for you.
Having an invasive ductal carcinoma generally doesn't affect prognosis. This type of cancer has a similar prognosis to the other main type, called invasive lobular carcinoma.
Things that can affect the prognosis for invasive ductal carcinoma and other breast cancers include:
After treatment, healthcare professionals often recommend making healthy choices that are good for anyone who wants improved health: Eat a balanced diet, exercise, maintain a weight that's healthy for you and limit the amount of alcohol you drink. For people with breast cancer, these healthy choices also might lower the risk of recurrent breast cancer.
Try to:
Talk with your healthcare team about other things you can do to lower your risk of recurrence. Also follow your care team's advice on follow-up exams and tests after you finish cancer treatment.
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